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FLASH GENE

Symbol

IRAK1

contributors: mct/ - updated : 13-07-2018

HGNC name	interleukin-1 receptor-associated kinase 1
HGNC id	6112

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --other   aberrantly expressed in the nucleus of the peripheral blood mononuclear cells from atherosclerosis patients

Susceptibility

to systemic lupus erythematosus

Variant & Polymorphism other	4 SNP haplotype (GGGG) being strongly associated with systemic lupus erythematosus, raising the possibility that the gender difference in SLE may in part be attributed to sex chromosome genes

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS