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FLASH GENE

Symbol

METTL1

contributors: mct/npt - updated : 05-11-2019

HGNC name	methyltransferase-like 1
HGNC id	7030

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       gain of function in hepatocellular carcinoma (HCC) and exhibits oncogenic activities via PTEN/AKT1 signaling pathway

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	serves as a promising prognostic biomarker in hepatocellular carcinoma (HCC)
Therapy target
	System Type Disorder Pubmed cancer digestive liver METTL1/PTEN axis may provide therapeutic potential in HCC intervention

ANIMAL & CELL MODELS