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FLASH GENE
Symbol TBX10 contributors: npt - updated : 16-12-2002
HGNC name T-box 10
HGNC id 11593
Location 11q13      Physical location : 67.398.774 - 67.407.031
Synonym name
  • T-box 7
  • T-box transcription factor TBX10
  • Synonym symbol(s) TBX7, TBX13
    DNA
    TYPE functioning gene
    STRUCTURE 8.00 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - TBX10 - D11S4087 - D11S916 - D11S4081 - qter
    Authors Law (98)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 1557 42 385 - Bush (2003)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestine    
    Lymphoid/Immunelymph node    
    Reproductivefemale systemuterus   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo, fetal, pregnancy
    Text kidney
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a large N terminal DNA binding domain (T-box)
  • HOMOLOGY
    interspecies homolog to murine T-box gene Tbx1 (T,brachyury)
    Homologene
    FAMILY
  • T-box family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • involved in the regulation of developmental processes
  • exhibits a unique spatio-temporal pattern during hindbrain development
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS development
    text regulation
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding through T-box
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS