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FLASH GENE
Symbol CPD contributors: - updated : 09-07-2007
HGNC name carboxypeptidase D
HGNC id 2301
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • B type membrane bound metallocarboxypeptidase comprising
  • three tandem active site domains, three CP domains
  • zinc peptide domain
    • conjugated MetalloP
    isoforms Precursor
    HOMOLOGY
    interspecies ortholog to duck gp180 (hepatitis virus-binding protein)
    ortholog to murine Cpd
    Homologene
    FAMILY zinc carboxypeptidase family, peptidase M14 family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    text localizd in the TGN (trans-Golgi network)
    basic FUNCTION carboxypeptidase, involved in secretory pathway
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    binds 2 zinc ions per subunit
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS