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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PLOD3

contributors: mct - updated : 20-06-2018

HGNC name	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
HGNC id	9083

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SCDEDS2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       gain of function in glioma tissues compared to normal brain tissues, and correlated with negative survival constitutional       loss of function in Recessive dystrophic epidermolysis bullosa

Susceptibility

Variant & Polymorphism

Candidate gene	might be a potential candidate for therapeutic applications in diseases associated with obesity and insulin resistance
Marker
Therapy target
	System Type Disorder Pubmed cancer brain glioma/neuroblstoma is a potential therapeutic target in human gliomas

ANIMAL & CELL MODELS