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FLASH GENE
Symbol ZNF189 contributors: npt - updated : 11-05-2009
HGNC name zinc finger protein 189
HGNC id 12980
Location 9q31.1      Physical location : 104.161.162 - 104.172.942
DNA
TYPE functioning gene
STRUCTURE 11.78 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text tissue or cell type restricted expression pattern for the splice variants, may be other transcripts
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - - 301 - - - Odeberg
- splicing 3002 71 612 not expressed in B cell lines Odeberg
splicing exon 1, missing exon 2
4 splicing 3280 68 584 not expressed in B cell lines Odeberg (1998)
splicing exon 1 initiation site exon 3
3 splicing 3186 73 626 not expressed in B cell lines Odeberg (1998)
splicing exon 1
- - - 62 531 - Odeberg
289bp deleted 5' of ZNF189d
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immunelymphocyte
cell lineage several, B cell lineages
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal, KRAB A domain
  • 16 C terminal zinc finger domains present in all transcripts
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • KRAB subfamily
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • transcriptional regulator
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS