Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CDH13

contributors: mct - updated : 15-02-2019

HGNC name	cadherin 13, H-cadherin (heart)
HGNC id	1753

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral   deletion     in lung carcinoma tumoral     --low   hypermethylated or deleted in ovarian, breast, lung and in colorectal cancer and adenoma tumoral     --low   in diffuse large B cell lymphomas (B-DLCLs) by promoter hyper-methylation tumoral     --low   by promoter hypermethylation is a common, early event in esophageal adenocarcinogenesis and correlates with clinical risk factors tumoral     --low   in cutaneous squamous cell carcinoma

Susceptibility

to Attention-deficit/hyperactivity disorder, ADHD to type 2 diabetes (T2DM)

Variant & Polymorphism SNP	association between the SNP-rs12596316 genotype and T2DM

Candidate gene	detection of methylation of the gene in blood might have utility in monitoring and detecting tumor recurrence in early-stage non-small cell lung cancer after curative surgical resection
Marker
Therapy target

ANIMAL & CELL MODELS

mice lacking Cdh13 exhibit reduced cognitive flexibility and loss of preference for contact region concomitant with increased reciprocal social interactions