Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|
| LOH
|
|
|
in retinoblastoma | tumoral
|
|
| --low
|
|
in breast cancer, correlated with a loss of the epithelial phenotype and with a gain of invasiveness | constitutional
|
|
| --other
|
|
down-modulation by potent antiinflammatory therapies in humans with arthritis may contribute to halting cartilage damage ( | tumoral
|
|
| --over
|
|
expression increasing from primary to metastatic disease in lymph nodes and especially bone | |