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FLASH GENE

Symbol

ERCC1

contributors: mct/pgu - updated : 06-06-2015

HGNC name	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
HGNC id	3433

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Ercc1-knockout mice, survive for up to 4 weeks after birth
	Ercc1 deficient mice show severe growth retardation associated with premature replicative senescence leading to liver failure and death at four weeks of age