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FLASH GENE

Symbol

ENO3

contributors: mct - updated : 21-08-2010

HGNC name	enolase 3, (beta, muscle)
HGNC id	3354

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	6.04 kb     12 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001976 12 - 1540 NP_001967 - 434 - Li (2004) NM_053013 12 - 1498 NP_443739 46.9 434 - Li (2004) NM_001193503 - - 1365 NP_001180432 42.12 391 - Li (2004)

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart       highly Digestive liver       highly Respiratory respiratory tract larynx     highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum     highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

mono polymer

homomer , dimer

HOMOLOGY

Homologene

FAMILY

enolase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm
text	localized to the z line

basic FUNCTION

having a function in striated muscle development and regeneration

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

glycolysis, energy pathway

a component

INTERACTION

DNA

RNA

small molecule	cofactor,
	magnesium, required for catalysis and for stabilizing the dimer

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

GSD13

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS