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FLASH GENE
Symbol ENO3 contributors: mct - updated : 21-08-2010
HGNC name enolase 3, (beta, muscle)
HGNC id 3354
Corresponding disease
GSD13 glycogen storage disease XIII
Location 17p13.2      Physical location : 4.854.383 - 4.860.425
Synonym name
  • 2-phospho-D-glycerate hydrolyase
  • ENO3, muscle enolase 3 beta
  • muscle specific enolase
    • Synonym symbol(s) MSE
    EC.number 4.2.1.11
    DNA
    TYPE functioning gene
    STRUCTURE 6.04 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 1540 - 434 - Li (2004)
    12 - 1498 46.9 434 - Li (2004)
    - - 1365 42.12 391 - Li (2004)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveliver   highly
    Respiratoryrespiratory tractlarynx  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatum  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , dimer
    HOMOLOGY
    Homologene
    FAMILY
  • enolase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    text localized to the z line
    basic FUNCTION
  • having a function in striated muscle development and regeneration
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    glycolysis, energy pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • magnesium, required for catalysis and for stabilizing the dimer
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) GSD13
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS