Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SCML1 contributors: mct - updated : 18-07-2008
HGNC name sex comb on midleg-like 1 (Drosophila)
HGNC id 10580
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two domains of homology with Drosophila transcriptional repressors of the polycomb PcG genes
  • SAM (sterile alpha motif) domain
    • HOMOLOGY
    interspecies homolog to Drosophila sex comb on midleg-like 1(member of polycomb group (PcG))
    homolog to Drosophila desat 1
    homolog to C.elegans Fat-7
    intraspecies homolog to SCML2
    Homologene
    FAMILY
  • SCM family
    • CATEGORY regulatory , DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in transcriptional repression of HOX genes
  • likely plays a role in testis development and spermatogenesis
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS development
    text embryogenesis and morphogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS