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FLASH GENE

Symbol

AMY2B

contributors: npt/ - updated : 02-02-2004

HGNC name	amylase, alpha 2B (pancreatic)
HGNC id	478

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
text	see AMY@
STRUCTURE	24.83 kb     12 Exon(s)

Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed AMY2B 12 - 2215 56 511 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver         Endocrine pancreas         Nervous brain         Reproductive male system prostate       Respiratory lung         Urinary kidney

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular endocrine   Epithelial secretory glandular exocrine   Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies	homolog to Drosophila Amy-d
	homolog to C.elegans C50B6.7

Homologene

FAMILY

glycosyl hydrolase 13 family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION

involved in the endohydrolysis of 1,4-alpha-glucosidic linkages in oligosaccharides and polysaccharides

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

digestion

PATHWAY

metabolism

carbohydrate

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding, cofactor,
	Ca2+
	chloride Cl2-

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS