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FLASH GENE

Symbol

ZIC3

contributors: mct/pgu - updated : 27-02-2013

HGNC name	Zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
HGNC id	12874

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

HTX1 , VACTERLX

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Zic3 null mice recapitulate the human heterotaxy phenotype but also have early gastrulation defects, axial patterning defects, and neural tube defects complicating an assessment of the role of Zic3 in cardiac development