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FLASH GENE
Symbol SC4MOL contributors: npt - updated : 03-12-2009
HGNC name sterol-C4-methyl oxidase-like
HGNC id 10545
Location 4q32.3      Physical location : 166.248.817 - 166.264.224
Synonym name
  • C-4 methyl sterol
  • methylsterol monooxygenase
  • Synonym symbol(s) DESP4, ERG25
    EC.number 1.14.13.72
    DNA
    TYPE functioning gene
    STRUCTURE 15.41 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    ANP32C 4q32.2 acidic (leucine-rich) nuclear phosphoprotein 32 family, member C LOC389239 4 similar to ring finger protein 129 LOC391709 4 similar to 60S ribosomal protein L26 LOC391710 4 similar to ring finger protein 129 LOC389240 4 similar to alpha NAC/1.9.2. protein LOC391711 4 similar to ring finger protein 129 FLJ31659 4q32.3 hypothetical protein FLJ31659 LOC391712 4 similar to ring finger protein 129 LOC391713 4 similar to ring finger protein 129 RNF129 4q32.3 ring finger protein 129 LOC391714 4 similar to ring finger protein 129 FLJ38482 4q32.3 hypothetical protein FLJ38482 KLHL2 4q21.2 kelch-like 2, Mayven (Drosophila) GKP3 4q32.1 glycerol kinase pseudogene 3 SC4MOL 4q32-q34 sterol-C4-methyl oxidase-like CPE 4q31 carboxypeptidase E HADHAP 4q32 hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase pseudogene (gastrin binding protein pseudogene) LOC285507 4q32.3 similar to chromosome 9 open reading frame 34 LOC391715 4 similar to RING finger protein 15 (Zinc finger protein RoRet) (Tripartite motif-containing protein 38) TLL1 4q32-q33 tolloid-like 1
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Endocrineadrenal gland    
     pancreas    
    Nervousgangliasensory gangliadorsal root  
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    Visualeye    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • histidine box domains
  • two potential N-glycosylation sites (Li 1996)
  • HOMOLOGY
    interspecies homolog to yeast ERG25
    Homologene
    FAMILY
  • sterol desaturase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • sterol-C4-methyl oxidaxe-like involved in cholesterol biosynthesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • iron
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS