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FLASH GENE

Symbol

DNTT

contributors: - updated : 12-07-2006

HGNC name	deoxynucleotidyltransferase, terminal
HGNC id	2983

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	34.00 kb     11 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

status

confirmed

Map

see WNT8B

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed V1 - - 2071 - 509 - Thai V2 - - 2068 - 508 - Thai

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune lymph node           thymus       highly Reproductive male system testis

cells

System Cell Pubmed Species Stage Rna symbol Lymphoid/Immune B cell

cell lineage
cell lines	malignant preB and preT lymphocytes
fluid/secretion

at STAGE

Text	in a restricted population of normal pre-B and pre-T lymphocytes during early differentiation,

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

BRCT adaptor domain,(BRCA1 C-terminus)

HOMOLOGY

Homologene

FAMILY

DNA polymerase type-X family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm
	intracellular,nucleus

basic FUNCTION

encoding a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	cofactor,
	magnesium

protein

interacting with PRPF19 and DNTTIP1

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS