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FLASH GENE
Symbol PSMC1 contributors: mct/npt - updated : 17-07-2008
HGNC name proteasome (prosome, macropain) 26S subunit, ATPase, 1
HGNC id 9547
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 1586 49 440 - Ewing (2007)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestivepharynx   highly
Endocrinepancreas   highly
Hearing/Equilibriumear   highly
Nervousbrain   highly
Reproductivefemale systemovary  highly
Respiratorylung   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connectivebone   
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Psmc1
homolog to Drosophila Pros26.4
homolog to C.elegans rpt.2
Homologene
FAMILY
  • PSM, proteasome family
  • AAA ATPase family
    • CATEGORY chaperone/stress , enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,nucleus
    basic FUNCTION
  • an ATPase-like subunit of the 19 S proteasome component
    • CELLULAR PROCESS protein, degradation
    protein, ubiquitin dependent proteolysis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • ATPase subunit of the 26 S (prosome-macropain) multicatalytic proteinase complex of proteasome
    • INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP
    • protein
  • interacts with HBX and PSMA7
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS