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FLASH GENE
Symbol GFRA3 contributors: mct/npt - updated : 07-07-2008
HGNC name GDNF family receptor alpha 3
HGNC id 4245
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 1980 44.5 400 - Wang (2006)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
 stomach    
Hearing/Equilibriumear   highly
Nervousbrainhindbraincerebellum predominantly
 gangliaautonomic gangliasympathetic  
 spinal cord    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsensory   
Nervousautonomous   
Nervouscentral   
Nervousperipherous   
cells
SystemCellPubmedSpeciesStageRna symbol
 nociceptive cell
not specificsensory ganglia
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
intraspecies homolog to GFRA1,GFRA2,GFRA4
Homologene
FAMILY
  • GDNFR family
    • CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    text anchored to the membrane by a C terminal glycosylphosphatidylinositol (GPI)-linkage
    basic FUNCTION
  • glycosylphosphatidylinositol linked cell surface receptor for artenin (ARTN) activating the RET receptor tyrosine kinase
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • artemin
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS