Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

CTBP1

contributors: mct - updated : 11-06-2015

HGNC name	C-terminal binding protein 1
HGNC id	2494

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   reduction of CTBP1 expression is correlated with migratory, invasive potential of melanoma cells

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer head and neck   potential chemo preventative or therapeutic strategy for head and neck squamous cell carcinomas (HNSCCs) by blocking NADH-dependent CTBP1 activity at early stages of HNSCC carcinogenesis cancer     potential target for therapeutic strategies for the treatment of cancer in general, and breast cancer in particular cancer digestive liver potential therapeutic target in human disease

ANIMAL & CELL MODELS