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FLASH GENE

Symbol

DSCAM

contributors: mct/npt/pgu - updated : 07-12-2013

HGNC name	Down syndrome cell adhesion molecule
HGNC id	3039

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

potentially involved in congenital heart disease

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	retinal ganglion cells (RGCs)had fasciculated dendrites and clumped cell bodies in Dscam(-/-) mice, suggesting a role in self-avoidance
	in Dscam deficient mice, retinal ganglion cells have defects in neuronal spacing and dendritic arborization patterns exhibiting neuronal self-avoidance phenotypes