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FLASH GENE
Symbol LMX1B contributors: mct/npt - updated : 30-05-2016
HGNC name LIM homeobox transcription factor 1, beta
HGNC id 6654
ASSOCIATED DISORDERS
corresponding disease(s) NPS1
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • dorsoventral limb patterning
  • Lmx1a/Lmx1b compound-null mutants fail to generate hindbrain roof plate
  • adult mice with an Lmx1b loss restricted to Hoxb8 neurons have nociception defects and disrupted organization of primary sensory afferent axons innervating the dorsal horn