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FLASH GENE
Symbol CSH2 contributors: - updated : 12-07-2006
HGNC name chorionic somatomammotropin hormone 2
HGNC id 2441
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing initiation site 883 25 217 placenta Palmetshofer
utilizing all five exons
- splicing initiation site 1134 18.8 167 placenta Palmetshofer
  • diverging in the C terminus due to a frameshift
  • putative TM domain
  • containing intron D
    • - splicing initiation site 598 13.9 122 placenta Palmetshofer
  • retaining the signal sequence
  • internal deletion;lacking exons 3,4
    • - splicing initiation site 437 - 23 - Palmetshofer
  • lacking exons 2,3,4
  • missing the signal sequence
    		•
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
    Endocrineneuroendocrinepituitary  highly
     thyroid   highly
    Hearing/Equilibriumear   highly
    Reproductivefemale systemplacenta  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta, chorion
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    intraspecies paralog to GH
    Homologene
    FAMILY somatotropin/prolactin family of hormones
    CATEGORY regulatory , signaling hormone
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION playing an important role in growth control
    CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling hormonal
    cell-cell signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other upregulated during development (isoforms 1 and 2)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS