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FLASH GENE

Symbol

HIST1H2AM

contributors: npt/ - updated : 12-02-2004

HGNC name	histone cluster 1, H2am
HGNC id	4735

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
text	N proximal cluster
STRUCTURE	0.49 kb     1 Exon(s)

regulatory sequence	Promoter (CAAT box) (TATA box)
text structure	two TATA boxes, four CAAT boxes and one H2B box in the intergenic promoter region

MAPPING

cloned

Y

linked

N

status

confirmed

regionally located

member of the small cluster of 16 histone genes located 2Mb centromeric to the major cluster of 35 histone genes

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed HIST1H2AM 1 - 487 14 130 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune thymus

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		basic
STRUCTURE

mono polymer

heteromer , octamer

HOMOLOGY

Homologene

FAMILY

histone H2A family

CATEGORY

DNA associated , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome,nucleosome

basic FUNCTION

playing a role in the compaction of DNA into nucleosomes

CELLULAR PROCESS	nucleotide, chromatin organization, remodeling
	nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

core histone H2A/H3B/H3/H4

INTERACTION

DNA	approximatively 0.146 kb

RNA

small molecule

protein	H2A
	H2B
	H3
	H4

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS