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FLASH GENE
Symbol CSH1 contributors: - updated : 03-05-2007
HGNC name chorionic somatomammotropin hormone 1 (placental lactogen)
HGNC id 2440
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Respiratorylung   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta, chorion
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
interspecies homolog to C.elegans C17B7.12
intraspecies paralog to GH
Homologene
FAMILY somatotrophin/prolactin family
CATEGORY secretory , signaling hormone
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION playing an important role in growth control
CELLULAR PROCESS cell life, proliferation/growth
PHYSIOLOGICAL PROCESS development
PATHWAY
metabolism
signaling hormonal , signal transduction
cell-cell signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
Other upregulated during development
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene hemizygosity of CSH1 in our population in comparison to controls indicates a role for CSH1 haploinsufficiency in the etiology of growth retardation
Marker
Therapy target
ANIMAL & CELL MODELS