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FLASH GENE

Symbol

HIST1H2AD

contributors: npt - updated : 20/11/2008

HGNC name	histone cluster 1, H2ad
HGNC id	4729

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
text	G distal cluster
STRUCTURE	0.46 kb     1 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

regionally located

in the large histone gene cluster

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed HIST1H2AD 1 - 460 14 130 - -

EXPRESSION

Type	ubiquitous

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		basic
STRUCTURE

motifs/domains

mono polymer

heteromer , octamer

HOMOLOGY

Homologene

FAMILY

histone H2A family

CATEGORY

DNA associated , transcription factor

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,nucleus,chromatin/chromosome,nucleosome

basic FUNCTION

playing a role in the compaction of DNA into nucleosomes

CELLULAR PROCESS	nucleotide, chromatin organization, remodeling
	nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

core histone H2A/H3B/H3/H4

INTERACTION

DNA	approximatively 0.146 kb

RNA

small molecule

protein	H2A
	H2B
	H3
	H4

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS