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FLASH GENE
Symbol GAMT contributors: mct/npt - updated : 07-01-2009
HGNC name guanidinoacetate N-methyltransferase
HGNC id 4136
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer monomer
HOMOLOGY
interspecies ortholog to murine Gamt
ortholog to rattus gamt
Homologene
FAMILY
  • RMT2 methyltransferase family
    • CATEGORY enzyme , motor/contractile
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • catalyzing the second and final step of the synthesis of creatine i.e. the transfer of a methyl group S-adenosylmethionine to guanidinoacetate
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism aminoacid , energetic
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) GAMTD
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS