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FLASH GENE
Symbol ETFDH contributors: mct/npt - updated : 13-10-2009
HGNC name electron-transferring-flavoprotein dehydrogenase
HGNC id 3483
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Digestiveliver   highly
 mouthtongue  highly
Lymphoid/Immunethymus   highly
Nervousbrain    
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • FAD binding domain
  • C terminal iron- sulfur binding domain
    • conjugated FlavoP
    mono polymer monomer
    isoforms Precursor 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane
    HOMOLOGY
    interspecies homolog to murine Etfdh
    Homologene
    FAMILY
  • ETF-QO/FIXC family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    basic FUNCTION
  • electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepting electrons from electron-transfer flavoprotein
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ETFDH
    related resource MITOP database
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS