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FLASH GENE

Symbol

KIR3DS1

contributors: mct - updated : 23-03-2013

HGNC name	killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
HGNC id	6340

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to rapid or delayed progresion of HIV1 to ankylosing spondylitis (AS)

Variant & Polymorphism other	interaction between KIR3DS1 and HLA-B (BW4-80Ileu) decreases progression of HIV1
	increased frequency of the KIR3DS1*013 allele in patients with AS is clearly independent of the presence of the HLA-Bw4I80 epitope

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS