| Symbol
| KIR3DL1
| contributors: mct - updated : 02-09-2011
|
| HGNC name
| killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
|
| HGNC id
| 6338
|
| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| constitutional
|
|
| --low
|
|
was able to enhance the regulatory function of Tregs and their ability to inhibit insulitis and T1Diabetes  | | constitutional
|
|
| --over
|
| |
in intestinal mucosa in active celiac disease | |
| Susceptibility
|
to ankylosing spondylitis |
| Variant & Polymorphism
other
| presence of the functional KIR3DL1 receptor has a protective effect on ankylosing spondylitis |
|
|
| 
|
Candidate gene
Marker
Therapy target
|
|
| System | Type | Disorder | Pubmed |
|---|
| diabete | type 1 | | |
| important target for modulation of Treg function for treatment of autoimmune diseases like T1Diabetes |
| | | |