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FLASH GENE
Symbol KIR2DS5 contributors: - updated : 10-04-2006
HGNC name killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
HGNC id 6337
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immuneactivated B lymphocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains two Ig extracellular domains and a short cytoplasmic tail
isoforms Truncated
HOMOLOGY
Homologene
FAMILY natural killer cell receptors family
CATEGORY immunity/defense , receptor membrane
SUBCELLULAR LOCALIZATION     plasma membrane
text type 1 membrane protein
basic FUNCTION
  • may be functioning as a receptor for class I molecules on NK cells
  • may be activating NK cell activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS