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FLASH GENE
Symbol KIR2DS5 contributors: - updated : 10-04-2006
HGNC name killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
HGNC id 6337
Location 19q13.4      Physical location : 98.111 - 113.132
Genatlas name natural killer cell immunoglobulin-like activating receptor for HLA-C antigens,2DS5
see FLNKR@
Synonym name associated transcript 9
Synonym symbol(s) NKAT9 ,K2S5
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text natural killer cell receptor cluster FLNKR@
STRUCTURE 14.00 kb     8 Exon(s)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
text alternatively spliced (truncated) forms (Dohring,1996)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immuneactivated B lymphocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains two Ig extracellular domains and a short cytoplasmic tail
isoforms Truncated
HOMOLOGY
Homologene
FAMILY natural killer cell receptors family
CATEGORY immunity/defense , receptor membrane
SUBCELLULAR LOCALIZATION     plasma membrane
text type 1 membrane protein
basic FUNCTION
  • may be functioning as a receptor for class I molecules on NK cells
  • may be activating NK cell activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS