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FLASH GENE
Symbol KIR2DS1 contributors: - updated : 10-04-2006
HGNC name killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
HGNC id 6333
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two extracellular immunoglobulin-like C2-type domains
  • a short cytoplasmic tail
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • natural killer cell receptors family
  • immunoglobulin superfamily
    • CATEGORY immunity/defense , receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type 1 membrane protein
    basic FUNCTION
  • functioning as a receptor for class I molecules on NK cells
  • activating NK cell activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to psoriasis
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS