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FLASH GENE
Symbol KIR2DS1 contributors: - updated : 10-04-2006
HGNC name killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
HGNC id 6333
Location 19q13.4      Physical location : 115.098 - 129.112
Genatlas name natural killer cell immunoglobulin-like activating receptor for HLA-C antigens, 2DS1, see FLNKR@
Synonym name CD158a - short form
Synonym symbol(s) p50.1, CD158H, EB6ActI, EB6ActII
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text natural killer cell receptor cluster FLNKR@
STRUCTURE 14.00 kb     8 Exon(s)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immuneactivated B lymphocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two extracellular immunoglobulin-like C2-type domains
  • a short cytoplasmic tail
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • natural killer cell receptors family
  • immunoglobulin superfamily
    • CATEGORY immunity/defense , receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type 1 membrane protein
    basic FUNCTION
  • functioning as a receptor for class I molecules on NK cells
  • activating NK cell activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to psoriasis
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS