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FLASH GENE
Symbol PHYH contributors: np/ - updated : 06-02-2006
HGNC name phytanoyl-CoA 2-hydroxylase
HGNC id 8940
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 1620 38.5 338 - 2005 15930519
8 splicing 1725 - 238 - 2005 15930519
different 5' utr and multiple differences in the coding region
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Urinarykidney    
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a cleavable peroxisomal targeting signal type 2 (PTS2)
    • HOMOLOGY
    Homologene
    FAMILY
  • PhyH family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • phytanoyl-CoA hydroxylase
  • first step of alpha-oxydation pathway of phytanic acid to pristanic acid
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism organic acid
    signaling sensory transduction/vision
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • iron Fe2+
  • 2 oxogluterate
    • protein
  • FKBP4
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) RDPA
    related resource Retinal Information Network
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS