Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

RS1

contributors: shn - updated : 17-04-2012

HGNC name	retinoschisin 1
HGNC id	10457

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	Pathologic changes in hemizygous Rs1h(-/Y) male mice are a marked splitting of the inner nuclear layer, a disorganization of the retinal cell layers, and a later degeneration of the photoreceptors whitch is more pronounced in cones
	Rs1h-KO mice display a thinned and disorganized outer nuclear layer, rod outer segments are misaligned and abundant schisis cavities spanned the inner nuclear, ERG a- and b-wave amplitudes are reduced by 33% and 50%, respectively