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FLASH GENE

Symbol

NDN

contributors: mct/npt - updated : 19-12-2018

HGNC name	necdin, MAGE family member
HGNC id	7675

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	NDN knockout mouse model(Lee,05)with defects seen in PWS patients
	Necdin-deficient mice display early post-natal lethality with variable penetrance
	Necdin-deficient mouse is the only model that reproduces the respiratory phenotype of PWS (central apnea and blunted response to respiratory challenges)