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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

GAK

contributors: mct - updated : 14-11-2017

HGNC name	cyclin G associated kinase
HGNC id	4113

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in both osteosarcoma cell lines and tissue samples when compared with human osteoblasts

Susceptibility

to Parkinson disease (PD)

Variant & Polymorphism other	GAK rs1564282 C/T polymorphism is associated with increased susceptibility to PD

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed neurology neurodegenerative Parkinson/dementia Parkinsonism is an attractive therapeutic target for the treatment of PD

ANIMAL & CELL MODELS