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FLASH GENE
Symbol HOXB4 contributors: - updated : 13-02-2004
HGNC name homeo box B4
HGNC id 5115
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
helix-turn-helix,DNA binding domain
HOMOLOGY
interspecies homolog to murine Hox-2.6
homolog to Drosophila Dfd
Homologene
FAMILY ANTP family of homeobox proteins
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • part of a developmental regulatory system that provides cells with positional identities on the anterior posterior axis
  • mediating marked enhancement of hematopoietic stem cell regeneration
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS