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FLASH GENE
Symbol BAT2 contributors: - updated : 10-07-2006
HGNC name HLA-B associated transcript 2
HGNC id 13918
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • very rich proline containing a DEAD box (Asp-Glu-Ala-Asp)
  • tracts of polyproline and charged aminoacids
    • conjugated PhosphoP
    HOMOLOGY
    interspecies ortholog to rattus Bat2 (90pc)
    ortholog to murine Bat2 (90.6pc)
    Homologene
    FAMILY DEAD family
    CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • acting as a putative helicase RNA, nuclear ATP dependent
  • may play a role in the regulation of pre-mRNA splicing
    • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • MHC
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility susceptibility gene for early onset IDDM (microsatellite repeats)
    Variant & Polymorphism
    Candidate gene for the development of rheumatoid arthritis
    Marker
    Therapy target
    ANIMAL & CELL MODELS