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FLASH GENE
Symbol AGPAT2 contributors: mct - updated : 13-10-2006
HGNC name 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
HGNC id 325
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four conserved motifs (I–IV), whose invariant residues appear to be important for catalysis and/or substrate recognition )
  • HOMOLOGY
    interspecies homolog to murine Agpat1
    intraspecies homolog to AGPAT1
    Homologene
    FAMILY
  • 1-acyl-sn-glycerol three phosphate acyltransferase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • lysophosphatidic acid acyltransferase (beta), catalyzing the conversion of lysophosphatidic acid to phosphatidic acid
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    second step in phospholipid biosynthesis, fatty acid and sterol
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) BSCL1
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS