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FLASH GENE
Symbol HOXB5 contributors: mct - updated : 24-02-2015
HGNC name homeobox B5
HGNC id 5116
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
enhances blood vessel perfusion by up-regulation of CCL2 and IL6 as well as in enhanced leucocyte infiltration and blood vessel remodelling
constitutional   deletion    
leads to anterior forelimb defects resulting from derepression of SHH expression
tumoral   amplification    
in oral squamous cell carcinoma
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS