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FLASH GENE
Symbol TEX28 contributors: shn/npt - updated : 17-12-2009
HGNC name testis expressed 28
HGNC id 2563
Location Xq28      Physical location : 153.498.932 - 153.523.438
Synonym name
  • chromosome X open reading frame 2
  • testis-specific protein TEX28
    • Synonym symbol(s) KIAA1854, CXorf2, fTEX
    DNA
    TYPE functioning gene
    SPECIAL FEATURE overlapping, opposite orientation
    text embedded in RGCP@, overlapping the most terminal GCP copy in opposite orientation and TKTL1, with other homologous repeated sequences in the cluster
    STRUCTURE 24.51 kb     5 Exon(s)
    text structure is a nested, intercalated gene within the red-green opsin cone pigment gene tandem array on Xq28
    MAPPING cloned Y linked N status provisional
    Map cen - DXS8061 - DXS8087 - TEX28 - DXS1073 - qter
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 1525 46 410 - Chen (2005)
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen   lowly
    Nervousnervecranial nerveoptic nerve highly
    Reproductivemale systemtestis  highly
    Urinarykidney   moderately
    Visualeyesclera  moderately
     eyeretina  highly
     eyeanterior segmentcornea lowly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text eye, lens, retina foveal, macular, eye anterior segment, RPE, choroid
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies ortholog to TEX28, pan troglodytes
    ortholog to Tex28, Rattus norvegicus
    ortholog to Tex28, Mus musculus
    Homologene
    FAMILY
  • TEX28 family
    • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism other TEX28 gene CNVs appear to be associated with the MYP1 X-linked myopia phenotypes
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS