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FLASH GENE

Symbol

HOXC13

contributors: mct - updated : 05-12-2012

HGNC name	homeo box C13
HGNC id	5125

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

EDHN3

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral fusion       fused with NUP98 in t(11;12) (p15;q13) in acute myeloid leukemia

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Hoxc13-null mice and transgenic Hoxc13-overexpressing mice presented with alopecia, indicating that Hoxc13 is a vital regulator in hair morphogenesis and postnatal cycling