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FLASH GENE
Symbol TFAP4 contributors: mct - updated : 24-04-2017
HGNC name transcription factor AP-4 (activating enhancer binding protein 4)
HGNC id 11745
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in primary neuroblastoma patients is associated with poor clinical outcome
tumoral     --over  
in primary colorectal cancer (CRC) significantly correlated with liver metastasis and poor patient survival
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancer  
inhibition of TFAP4 function may represent a therapeutic approach to block tumor cell proliferation
ANIMAL & CELL MODELS