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FLASH GENE
Symbol DNASE1L2 contributors: - updated : 19-07-2004
HGNC name deoxyribonuclease I-like 2
HGNC id 2958
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 21AA signal peptide
  • a proline-rich domain
    • HOMOLOGY
    interspecies homolog to murine Dnase1
    intraspecies homolog to dnase1
    Homologene
    FAMILY DNAse 1 family of endonuclease
    CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION
    basic FUNCTION having a divalent cation-dependent acidic endonuclease activity
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism nucleic
    signaling
    nucleotide
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by TNFA aand IL1Bvia the nuclear NFKB
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS