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FLASH GENE
Symbol TUBA8 contributors: mct/npt - updated : 03-12-2009
HGNC name tubulin, alpha 8
HGNC id 12410
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Tuba8
Homologene
FAMILY
  • tubulin family
    • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule
    basic FUNCTION
  • major constituent of microtubules
  • may be playing a role in regulating mammalian brain development (Abdollahi 2009)
  • participates in microtubule assembly in mammalian cells (Abdollahi 2009)
  • implicated in a specific aspect of cerebral cortical development (Abdollahi 2009)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PMGOH
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS