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FLASH GENE
Symbol TUBA8 contributors: mct/npt - updated : 03-12-2009
HGNC name tubulin, alpha 8
HGNC id 12410
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Nervousbrainforebraincerebral cortex highly
Reproductivemale systemtestis   
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connective    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
Text widely expressed in developing neural structures (Abdollahi 2009)
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Tuba8
Homologene
FAMILY
  • tubulin family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule
    basic FUNCTION
  • major constituent of microtubules
  • may be playing a role in regulating mammalian brain development (Abdollahi 2009)
  • participates in microtubule assembly in mammalian cells (Abdollahi 2009)
  • implicated in a specific aspect of cerebral cortical development (Abdollahi 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PMGOH
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS