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FLASH GENE
Symbol GGT1 contributors: npt - updated : 24-08-2007
HGNC name gamma-glutamyltransferase 1
HGNC id 4250
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolonsigmoid 
Respiratorylung    
Skin/Tegumentskin    
Visualeye    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • precursor cleaved, a heavy and a light chain (351 and 189AA)
  • isoforms Precursor
    HOMOLOGY
    interspecies homolog to murine Ggtp
    intraspecies homolog to GGT2
    Homologene
    FAMILY
  • gamma-glutamyltransferase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type 2 membrane protein
    basic FUNCTION
  • transfer of the glutamyl moiety of glutamine to a variety of AAs and adipocytes acceptors
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism aminoacid
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) GGT1
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS