Symbol
| MAGEA4
| contributors: mct/npt - updated : 04-06-2020
|
HGNC name
| melanoma antigen family A, 4
|
HGNC id
| 6802
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
| --over
|  
|
in non-small cell lung carcinomas (Peikert 2006) | tumoral
|  
|  
| --over
|  
|
in primary breast cancer | tumoral
|  
|  
| --over
|  
|
in a variety of malignancies in significant correlation with tumor cell invasiveness and aggressiveness | tumoral
|  
|  
| --over
|  
|
in patients with synovial sarcoma | tumoral
|  
|  
| --other
|  
|
MAGEA4 immunohistochemical expressionis associated with decreased disease free and overall survival in patients with high-grade endometrial cancer | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
| potential utility of MAGEA4 as an ancillary diagnostic marker for synovial sarcoma combined with CTAG1B | |
CTAG1B and MAGEA4 may be useful for the diagnosis of synovial sarcoma | Therapy target
| | |