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FLASH GENE
Symbol MAGEA4 contributors: mct/npt - updated : 04-06-2020
HGNC name melanoma antigen family A, 4
HGNC id 6802
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in non-small cell lung carcinomas (Peikert 2006)
tumoral     --over  
in primary breast cancer
tumoral     --over  
in a variety of malignancies in significant correlation with tumor cell invasiveness and aggressiveness
tumoral     --over  
in patients with synovial sarcoma
tumoral     --other  
MAGEA4 immunohistochemical expressionis associated with decreased disease free and overall survival in patients with high-grade endometrial cancer
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • potential utility of MAGEA4 as an ancillary diagnostic marker for synovial sarcoma combined with CTAG1B
  • CTAG1B and MAGEA4 may be useful for the diagnosis of synovial sarcoma
  • Therapy target
    ANIMAL & CELL MODELS