Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | KRT12 | contributors: mct/npt/shn - updated : 03-04-2011 |
HGNC name | keratin 12 |
HGNC id | 6414 |
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Corresponding disease |
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Location | 17q21.2 Physical location : 39.017.429 - 39.023.462 | ||
Synonym name | |||
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Synonym symbol(s) | K12 |
DNA |
TYPE | functioning gene |
STRUCTURE | 6.03 kb 8 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | Y | status | confirmed |
Map | cen - D17S1814 - D17S1299 - KRT12 - D7S800 - D17S1787 - qter |
Authors | Irvine (97) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
constitutive of | cornea specific |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | embryo, fetal |
Text | corneal differentiation, eye, lens, anterior segment, optic nerve, retina, RPE, choroid |
PROTEIN |
PHYSICAL PROPERTIES | acid | |
STRUCTURE |
mono polymer | heteromer , tetramer |
HOMOLOGY |
interspecies | ortholog to KRT12, Pan troglodytes |
ortholog to Krt12, Rattus norvegicus | |
ortholog to Krt12, Mus musculus |
Homologene |
FAMILY | |
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CATEGORY | structural protein |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytoskeleton,intermed filament |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | sensory transduction/vision |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | CDM2 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |